Reference #: 1007878 SHIFT:Day (United States of America)

Seeking Breakthrough Makers

Children's Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation.

At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care-and your career.

CHOP's Commitment to Diversity, Equity, and Inclusion

CHOP is committed to building an inclusive culture where employees feel a sense of belonging, connection, and community within their workplace. We are a team dedicated to fostering an environment that allows for all to be their authentic selves. We are focused on attracting, cultivating, and retaining diverse talent who can help us deliver on our mission to be a world leader in the advancement of healthcare for children.

We strongly encourage all candidates of diverse backgrounds and lived experiences to apply.

A Brief Overview A research technician position is available in the laboratory of Dr. Brad Lindell within the Department of Anesthesia and Critical Care at Children's Hospital of Philadelphia. Dr. Lindell is a pediatric intensivist who studies mechanisms of immune dysfunction in critically ill pediatric patients in collaboration with clinical and translational scientists throughout CHOP and UPenn.

In this position, candidates will employ a range of cellular immunology techniques, including spectral flow cytometry, mass cytometry, transcriptomics, metabolomics, and mitochondrial function assays using human biospecimens. We then apply a systems immunology approach to this multimodal data to develop mechanistic hypotheses of human immune dysfunction in the setting of critical illness.

OVERALL RESPONSIBILITIES: After a period of in-lab training by the principal investigator, the applicant will be responsible for independently performing complex immunological assays using fresh and cryopreserved human biospecimens. The candidate will function under the general guidance of the principal investigator, and as part of a team. Depending on candidate background and interest, they may also participate in the writing of project plans, grants, and scientific publications.

Candidates must have at least one year of laboratory experience in immunology, cellular and molecular biology, or related fields. Competitive candidates will have experience in flow cytometry, RNA-seq, and translational immunology. Project leadership experience and excellent communication and organizational skills are fundamental to this position. Salary is competitive and will depend upon qualifications and previous training. Institutional assistance obtaining a visa to work in the United States is available. Applicants from backgrounds underrepresented in biomedical research are especially encouraged to apply

What you will do Performs research procedures on experimental samples with minimal supervision Formulates and performs complex lab experiments and analyzes/ reports the data Performs tasks that require knowledge of advanced techniques and lab equipment Performs advanced calculations and maintains appropriate log and lab notebooks Assists with planning specific research protocols and procedures Assists in development & troubleshooting of new techniques and ideas May be required to modify scientific methods and protocols (in conjunction with PI) Checks others' results for completeness and accuracy May be responsible for training and mentoring new staff May assist in the preparation of grants journal articles, posters and oral presentations May perform routine and non-routine tests / experiments as needed Maintains office, lab area, reagents, supplies and equipment Performs routine maintenance on lab equipment Coordinates schedules of tests & procedures Atte ds courses, seminars, and lab meetings to expand knowledge of research and laboratory techniques Records results, organizes data and maintains lab notebook in an organized manner Conducts literary searches as required Education Qualifications High School Diploma / GED Required Bachelor's Degree Preferred Experience Qualifications At least two (2) years of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience Required At least three (3) years of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience Preferred Skills and Abilities Advanced understanding of lab procedures, protocols, and equipment. Intermediate proficiency with lab specific experiments / techniques. Intermediate scientific analysis skills. Excellent verbal and written communications skills Excellent organizational skills Strong critical thinking / problem-solving skills Strong analytical skills

To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must be fully vaccinated against COVID-19 and receive an annual influenza vaccine.

Employees may request exemptions for valid religious and medical reasons. Start dates may be delayed until candidates are immunized or exemption requests are reviewed.

|

Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.