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The Children's Hospital of Philadelphia Research Post-Doc Fellow - Genetic Skeletal Disorders - Lefebvre Lab in Philadelphia, Pennsylvania

Reference #: 1009413 SHIFT:Day (United States of America)

Seeking Breakthrough Makers

Children's Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation.

At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care-and your career.

CHOP's Commitment to Diversity, Equity, and Inclusion

CHOP is committed to building an inclusive culture where employees feel a sense of belonging, connection, and community within their workplace. We are a team dedicated to fostering an environment that allows for all to be their authentic selves. We are focused on attracting, cultivating, and retaining diverse talent who can help us deliver on our mission to be a world leader in the advancement of healthcare for children.

We strongly encourage all candidates of diverse backgrounds and lived experiences to apply.

A Brief Overview Assume responsibility for an on-going, innovative research project as a Postdoctoral Fellow at CHOP. Our postdoc experience will broaden your skillset, scientific background, and research capabilities.

CHOP's Commitment to Diversity, Equity, and Inclusion CHOP is committed to building an inclusive culture where employees feel a sense of belonging, connection, and community within their workplace. We are a team dedicated to fostering an environment that allows for all to be their authentic selves. We are focused on attracting, cultivating, and retaining diverse talent who can help us deliver on our mission to be a world leader in the advancement of healthcare for children.

We strongly encourage all candidates of diverse backgrounds and lived experiences to apply.

Responsibilities * Participate in project planning, recording, and evaluation of data. * Conduct independent scholarly research, developing new methods and protocols under the guidance of a mentor (principal investigator). * Acquire technical, lab management, and grant writing skills. * Participate in seminars, lectures, poster sessions, national presentations, and professional workshops. * Supervise junior lab members. * Assist with other research projects as needed. Education Qualifications Doctorate (required)

About the Laboratory A postdoctoral fellow position is available in the Lefebvre laboratory in the Translational Research Program in Pediatric Orthopaedics at the Children's Hospital of Philadelphia (CHOP) Abramson Research Institute.

The fellow will contribute to a research project aiming at elucidating cellular and molecular mechanisms underlying genetic skeletal dysplasias, including achondroplasia and campomelic dysplasia, and at developing gene therapy approaches to alleviate the clinical manifestations of these disorders and improve the quality of life of affected individuals. The fellow will use cutting-edge approaches in vivo and in vitro, including mouse models, human iPSC-derived organoid models, high-throughput 'omics' approaches and gene therapy strategies. Successful accomplishment of this research is anticipated to deepen fundamental scientific knowledge and to increase our understanding of mechanisms underlying skeletal dysplasias. It is also anticipated to help the fellow launch a promising career as an independent research investigator.

Strong candidates for this position will be eager to contribute to pioneering translational research. They will have obtained a Ph.D. degree in the last three years and will have a solid scientific background and a strong publication record relevant to the project. They will also have outstanding communication skills and first-rate interpersonal and organizational skills. Candidates should send their curriculum vitae, a description of research interests and career goals, and contac information for three or more Faculty-level references to Dr. Veronique Lefebvre (lefebvrev1@chop.edu).

To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must be fully vaccinated against COVID-19 and receive an annual influenza vaccine.

Employees may request exemptions for valid religious and medical reasons. Start dates may be delayed until candidates are immunized or exemption requests are reviewed.

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Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.

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