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The University of Miami Miller School of Medicine, Department of Medicine – Division of Gastroenterology, has an exciting opportunity for a Postdoctoral Associate to study innate immune regulation in the intestine with a focus on the role of TLR4 signaling in colonic neoplasia. This laboratory is under the direction of Dr. Maria Abreu located on the Medical Campus. Animal models, human tissues, and in vitro systems are used to examine the molecular regulation innate immune receptors in health and disease, especially inflammatory bowel diseases. The laboratory is also interested in the intersection between innate immunity, the microbiome, and the development of intestinal cancer. Germ-free animal models will be used to examine the role of host-bacterial interactions in intestinal homeostasis, inflammation, and cancer.

• Carrying out animal experiments in models of colitis, particularly mice.

• Carrying out primary epithelial and immunocyte cell culture on human and mouse tissues.

• Performing DNA/RNA extraction and protein purification, PCR, qPCR, Primer Designing, PAGE, Western blot, flow cytometry, Elisa, cell culture, organoid culture, ROS measurement, Glucose tolerance test, Evaluation of inflammation in tissue samples.

• Assisting in the design and planning of experiments in collaboration with other labs and other laboratory members.

• Being able to assist and organize tasks for laboratory assistants.

• Collecting and analyzing data into written and graphical formats for publication, presentation in meetings, and grant applications.

• Participate at local and national scientific conferences by writing abstracts that summarize scientific findings and preparing posters or oral presentations.

• Being able to interpretate RNA/DNA seq data from public databases or results of experiments obtained in the lab.

This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary.

MINIMUM QUALIFICATIONS

• Ph.D. required in Molecular Biology, Immunology or related field.

• No previous experience required.

• Prefer 2-3 years previous experience working in a basic science laboratory.

​Knowledge, Skills and Attitudes:

• Demonstrated adequate command of English is required (written and verbal).

• Experience with molecular biology and immunology-based laboratory techniques such as PCR, Western blots, Elisa, DNA/RNA extraction and protein purification, PAGE, flow cytometry, cell culture, organoid culture, ROS measurement, Glucose tolerance test, Evaluation of inflammation in tissue samples.

• Participate at local and national scientific conferences by writing abstracts that summarize scientific findings and preparing posters or oral presentations.

• Being able to interpretate RNA/DNA seq data from public databases or results of experiments obtained in the lab.

• Excellent sterile technique to work with cell and tissue culture is required.

• Good mouse handling technique and experience in mouse models preferred.

• Being organized, responsible, tidy, motivated and enthusiastic for basic research.

• Able to work well as a team.

• Working knowledge of the microbiome to integrate with epithelial biology

The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more.

UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for.

Patient safety is a top priority. As a result, during the Influenza ("the flu") season (September through April), the University Of Miami Miller School Of Medicine requires all employees who provide ongoing services to patients, work in a location (all Hospitals and clinics) where patient care is provided, or work in patient care or clinical care areas, to have an annual influenza vaccination. Failure to meet this requirement will result in rescinding or termination of employment.

The University of Miami is an Equal Opportunity Employer - Females/Minorities/Protected Veterans/Individuals with Disabilities are encouraged to apply. Applicants and employees are protected from discrimination based on certain categories protected by Federal law. Click here (https://www.hr.miami.edu/careers/eo-ada/index.html) for additional information.

Job Status:

Full time

Employee Type:

Research-Limited Term

Pay Grade:

A9

The mission of the University of Miami is to transform lives through education, research, innovation, and service. A vibrant and diverse academic and healthcare community, the University of Miami and the University of Miami Health System ("UHealth") have rapidly progressed to become one of the nation’s top research universities and academic medical centers in the nation.

The University comprises 12 schools and colleges serving undergraduate and graduate students in more than 350 majors and programs. Visit welcome.miami.edu/about-um to learn more about our points of pride.

The University ranks No. 55 on U.S. News & World Report’s 2022 Best Colleges list and ranked No. 49 in the 2022 Wall Street Journal/Times Higher Education College Rankings.

Bascom Palmer Eye Institute is ranked the #1 eye hospital in the USA and offers some of the nation's premiere eye doctors to treat every eye condition for adults. Sylvester Comprehensive Cancer, part of the Miller School of Medicine, received the prestigious National Cancer Institute designation in 2019.

The University of Miami and UHealth have also ranked among the Forbes Best Employers and Best Employers for Women on several occasions, most recently in 2022.

Transforming lives

With more than 17,000 faculty and staff, the University strives for excellence, and is driven by a powerful mission to transform and impact the lives of its students, patients, members of the community, and people across the globe.

The University is committed to fostering a culture of belonging, where everyone feels valued and has the opportunity to add value. Through values of Diversity, Integrity, Responsibility, Excellence, Compassion, Creativity, and Teamwork (DIRECCT) the U community works together to create an environment driven by purpose, excellence, community, and service.