Thermo Fisher Scientific Scientist III, Analytical & Formulation Sciences in St. Louis, Missouri
When you’re part of the team at Thermo Fisher Scientific, you’ll do important work, like helping customers in finding cures for cancer, protecting the environment or making sure our food is safe. Your work will have real-world impact, and you’ll be supported in achieving your career goals.
The Process Development Scientist opportunity will be in the Analytical & Formulations Sciences department Cell Based Assay & Electrophoresis group and reside in St. Louis, Missouri.
How will you make an impact?
Provides complex analyses in a biology environment by selecting appropriate methods with independent judgment. Performs cell-based analytical methods for complex testing to support process development and/or manufacturing operations. May research and implement new methods and technologies to enhance operations. Makes detailed observations and analyzes, resolves issues, documents, and communicates test results.
What will you do?
Knowledge and experience with cell-based assays, including cytotoxicity, proliferation, ADCC and report-gene assays. Broad experience with mammalian cell lines and culture techniques. Experience with colorimetric, fluorescent and luciferase-based methods.
Performs complex analytical methods and studies to support method and formulation development, structural characterization, comparability, forced degradation, and other development activities of biopharmaceuticals at all stages of clinical development.
Designs experimental plans based on the defined deliverables.
Develops, qualifies, and transfers analytical methods. Works with Quality Control to trouble-shoot and improve existing analytical methods.
Clearly and accurately communicates the results of work by creating documentation of the testing/analysis and obtained results. Records results in notebook accurately, clearly, and regularly.
Recognizes and reports unexpected results and non-routine analytical and product problems; recommends solutions.
Prepares protocols, reports, and test methods and writes SOPs.
Maintains and troubleshoots analytical instrumentation as needed. Helps to maintain laboratory and order common supplies.
Remains current in the field by review of relevant scientific literature and attendance at appropriate scientific seminars and conferences.
Performs all duties in compliance with Standard Operating Procedures, Good Manufacturing Practices, Good Laboratory Practices, and Safety guidelines. Maintains the necessary compliance status required by company and facility standards.
Ability to function in a rapidly changing environment and balance multiple priorities moving from one project to another as priorities change.
How will you get here?
- Bachelor's degree or Master’s degree or PhD in molecular cell biology, biochemistry, or a related field.
With Bachelor’s degree, minimum of 5 years of experience related to pharmaceutical manufacturing, process, development or academic laboratory.
With Master's degree, minimum of 2 years of experience related to pharmaceutical manufacturing, process, development or academic laboratory.
With PhD, experience with practical scientific application necessary, though related experience not necessary.
Relevant industry experience preferred.
Equivalent combinations of education, training, and relevant work experience may be considered.
Knowledge, Skills, Abilities
Deep knowledge of varied aspects or a specialized aspect of discipline.
Working knowledge of GMP/GLP regulations in cGMP/cGLP manufacturing environment preferred. Solid lab skills.
Good writing, communication and presentation skills.
Solid MS Excel, PowerPoint and Word skills.
Excellent problem solving and critical thinking skills. Excellent organization and planning skills.
Strong attention to detail and ability to adhere to standard procedures.
Ability to design and execute tasks and studies based on the deliverables.
Ability to analyze and summarize complex scientific data.
Ability to properly document work and write reports.
Ability to function in a rapidly changing environment.
Ability to speak effectively before groups of customers and employees. Ability to make decisions that require choosing between limited alternatives to resolve complex problems. Ability to lead and mentor less experienced staff.
Ability to read, analyze, and interpret general business periodicals, professional journals, technical procedures, or governmental regulations.
Position requires ordinary ambulatory skills and physical coordination sufficient to move about office and lab locations; ability to stand, walk, stoop, kneel, crouch periodically for prolonged periods of time; manipulation (lift, carry, move) of light to medium weights of 10-35 pound pounds; arm, hand and finger dexterity, including ability to grasp and type for prolonged periods of time; visual acuity to use a keyboard, computer monitor, operate equipment, and read materials for prolonged periods of time; ability to sit, reach with hands and arms, talk, and hear for prolonged periods of time. Stand up to 50% daily. Walk within lab and between buildings daily. Repetitive hand motions.
At Thermo Fisher Scientific, each one of our 70,000 extraordinary minds has a unique story to tell. Join us and contribute to our singular mission—enabling our customers to make the world healthier, cleaner and safer.
If you are an individual with a disability who requires reasonable accommodation to complete any part of our application process, click here at https://jobs.thermofisher.com/page/show/eeo-affirmative-action-statement#accessibility for further assistance.
Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.